Analytical Data
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基因名
IL-4
- Application
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别名
B-cell stimulatory factor 1
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P05112
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表达区间
25-153aa
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分子量
31 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Interleukin-4 (IL-4) is a crucial cytokine primarily produced by activated T cells, mast cells, and basophils, playing a pivotal role in immune regulation and inflammation. Research into IL-4 has gained considerable attention due to its significant functions in promoting B cell differentiation, enhancing IgE production, and influencing the polarization of T helper cells towards a Th2 phenotype, which is associated with allergic responses and asthma. The recombinant form of IL-4 serves as a valuable tool in biomedical research, enabling the study of its signaling pathways and physiological effects. Furthermore, understanding IL-4's role in various diseases, such as allergies, asthma, and certain cancers, has opened avenues for therapeutic interventions. Researchers have been investigating IL-4's potential as a therapeutic agent in modulating immune responses and developing vaccines. The recombinant IL-4 protein can also serve as an essential component in the development of immunotherapies, aimed at harnessing the immune system to combat diseases. As such, the continued exploration of IL-4 and its recombinant form is integral for the advancement of both basic immunology and clinical applications.
