Analytical Data
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基因名
PI15
- Application
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别名
P25TI; CRISP-8; 25 kDa trypsin inhibitor; Cysteine-rich secretory protein 8
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O43692
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表达区间
Ser20~Lys258
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分子量
31kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PI15, or Proteinase Inhibitor 15, is a serine protease inhibitor predominantly expressed in various tissues, including the skin and the digestive system. It plays a critical role in regulating proteolytic activity, which is essential for maintaining homeostasis and modulating inflammatory responses. Research has shown that PI15 is involved in protecting cells against proteolysis, which can lead to tissue damage and chronic inflammation if left unchecked. Additionally, PI15 has garnered interest due to its potential implications in metabolic disorders and cancer, as it may influence tumor progression by modulating the extracellular matrix and impacting cell migration. Understanding the structure and function of PI15 at the molecular level is crucial for elucidating its role in physiological and pathological processes. Recent advancements in biotechnology have facilitated the recombinant production of PI15, providing a valuable tool for studying its mechanism of action and exploring its therapeutic potential. These studies aim to harness PI15 as a biomarker for disease diagnosis and as a target for novel therapeutic strategies, highlighting its significance in health and disease. The ongoing research into PI15 not only enhances our understanding of protease inhibition but also opens new avenues for the development of innovative treatments for various conditions associated with protease dysregulation.












