Analytical Data
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基因名
HIP1
- Application
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别名
ILWEQ
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O00291
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表达区间
Leu817~Glu1037
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分子量
33kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HIP1 (Huntingtin Interacting Protein 1) is a protein that has gained attention due to its role in various cellular processes, including endocytosis, intracellular trafficking, and particularly its interaction with the huntingtin protein, which is implicated in Huntington’s disease. Research into HIP1 has revealed its involvement in the regulation of synaptic function and its potential impact on neurodegenerative disorders. Studies suggest that HIP1 may influence neuronal survival and plasticity, making it a significant candidate for understanding the pathophysiology of Huntington’s disease and other neurodegenerative conditions. Moreover, HIP1 has been associated with the modulation of cellular signaling pathways, indicating its potential as a therapeutic target. As researchers continue to explore the functional implications of HIP1 and its protein interactions, the generation of recombinant HIP1 proteins has become essential for studying its biological roles and developing potential treatments for diseases linked to its dysfunction. This research background highlights the importance of HIP1 in neuroscience and the broader implications it may have for understanding and treating neurodegenerative diseases.












