Analytical Data
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Gene name
CAPN6
- Application
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Alternative Names
CAPNX; CalpM; CANPX; Calpamodulin; Calpain-like protease X-linked
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y6Q1
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Expression Region
Leu26~Arg495
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Molecular Weight
59kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CAPN6, a member of the calpain family, plays a crucial role in various cellular processes, including cell differentiation, apoptosis, and signal transduction. Unlike other calpain family members, CAPN6 is characterized by a unique expression pattern, primarily found in certain tissues such as the brain and skeletal muscle. Its significance has been increasingly recognized in the context of various diseases, including muscular dystrophies and neurodegenerative disorders. Recent studies have highlighted CAPN6's potential as a modulator of cellular pathways linked to inflammation and muscle regeneration. Given its distinct properties and potential therapeutic implications, researchers have focused on producing recombinant CAPN6 proteins to elucidate its functional mechanisms. This involves advanced molecular biology techniques to express and purify CAPN6, enabling detailed biochemical and biophysical characterizations. Understanding CAPN6's structure and function is essential for unraveling its role in disease and developing targeted therapies. Thus, the study of CAPN6 recombinant protein is not only vital for basic research but also holds promise for future clinical applications.
