Cat: IPD-X38869

Recombinant Human UCP4 Protein,His

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Analytical Data

  • 基因名

    UCP4

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    SLC25A27; Solute Carrier Family 25 Member 27

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O95847

  • 表达区间

    Ser21~Met317

  • 分子量

    34kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

UCP4 (Uncoupling Protein 4) is a member of the uncoupling protein family, which plays a crucial role in thermogenesis and energy metabolism within mitochondria. Identified primarily in the brain and testis, UCP4 is believed to be involved in the regulation of reactive oxygen species (ROS) and mitochondrial membrane potential, thereby influencing cellular energy homeostasis. Research into UCP4 has gained momentum due to its potential implications in neurological conditions and metabolic disorders. The study of UCP4 recombinant protein is critical for understanding its function and mechanism of action at a molecular level. Recombinant UCP4 can be produced in various expression systems, enabling detailed biochemical assays and functional studies. Moreover, the exploration of UCP4's interaction with other mitochondrial proteins and its regulatory features could unveil therapeutic targets for diseases associated with mitochondrial dysfunction, such as neurodegenerative disorders. Advances in biotechnology have made it feasible to generate UCP4 in a pure form, allowing researchers to investigate its contribution to mitochondrial physiology and its potential role in energy dysregulation. As the relationship between mitochondrial function and health becomes clearer, UCP4 is positioned as a promising focal point in the quest to devise novel treatments for diseases rooted in energy metabolism disruptions.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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