Analytical Data
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基因名
PCDHa10
- Application
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别名
CNR8; CRNR8; CNRN8; CNRS8
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y5I2
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表达区间
Gln29~Pro219
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分子量
25kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PCDHa10, a member of the protocadherin gene family, plays a pivotal role in the development and maintenance of the nervous system, particularly in establishing neuronal connections and synaptic specificity. Research on PCDHa10 has gained momentum due to its potential implications in neurological diseases and disorders. This protein is characterized by its unique extracellular cadherin-like domains, which are critical for cell-cell adhesion and signaling. The expression patterns of PCDHa10 suggest that it may influence neuronal identity and connectivity during brain development. Recent studies have indicated that alterations in PCDHa10 expression can lead to neurodevelopmental abnormalities, linking it to conditions such as autism spectrum disorder and schizophrenia. Additionally, PCDHa10 serves as a valuable model for understanding the molecular mechanisms underlying synaptic integration and plasticity. Consequently, recombinant research on PCDHa10 aims to elucidate its structural and functional properties, paving the way for therapeutic interventions targeting its pathways to address related neurological issues. As such, elucidating the biological functions of PCDHa10 through recombinant protein studies is critical for advancing our understanding of its role in neurobiology and for developing potential strategies to mitigate the impact of neurological disorders associated with its dysfunction.












