Analytical Data
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Gene name
PCDHa9
- Application
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q91Y11
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Expression Region
Gln60~Ser317
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Molecular Weight
33kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PCDHa9, a member of the protocadherin alpha (PCDH) gene family, has garnered attention in recent neuroscience research due to its potential role in neural development and synaptic connectivity. Protocadherins are cell adhesion molecules that are predominantly expressed in the brain and are involved in establishing and maintaining the complex networks of neural connections. PCDHa9, specifically, is expressed in specific neuronal populations, suggesting its involvement in mediating interactions between neurons. Aberrant expression or mutations in protocadherins have been linked to various neurodevelopmental disorders, including autism spectrum disorders and schizophrenia, highlighting the need to understand their functional mechanisms. The recombinant study of PCDHa9 protein focuses on elucidating its structure-function relationship, interactions with other neural proteins, and its role in cellular signaling pathways. By producing and characterizing recombinant PCDHa9 protein, researchers aim to explore its adhesive properties, cellular localization, and the effects of its expression levels on neuronal behavior. This research not only advances our understanding of PCDHa9's function in the brain but also holds promise for potential therapeutic strategies targeting related neurological conditions. As such, the study of PCDHa9 recombinant protein is critical for unraveling the complexities of neuronal networks and the molecular underpinnings of brain function and development.
