Analytical Data
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基因名
PCDHgA11
- Application
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别名
Pcdh6; Protocadherin-6
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y5H2
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表达区间
Arg30~Asn176
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分子量
22kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PCDHgA11, a member of the protocadherin gene family, plays a crucial role in neuronal connectivity and the establishment of synaptic specificity in the central nervous system. This protein is encoded by the PCDHGA11 gene, which is located in a cluster on chromosome 5 that is associated with cell-cell adhesion and signal transduction processes. Research has revealed that protocadherins, including PCDHgA11, contribute to the development of brain regions and are involved in neurodevelopmental disorders. Given its potential implications in synaptic function and neuronal circuit formation, recombinant PCDHgA11 protein has garnered attention as a subject of investigation. Scientists aim to elucidate its structural characteristics and functional mechanisms to better understand its role in neural networks. Furthermore, studying this protein may provide insights into the pathophysiological mechanisms underlying various neurological conditions, making PCDHgA11 an important target for therapeutic interventions. Through the production of recombinant PCDHgA11, researchers can conduct detailed biochemical assays, structural analyses, and functional studies to explore its interactions with other neural proteins and potentially identify its role in synaptic plasticity and cognitive functions. The findings could also contribute to the development of strategies aimed at mitigating the effects of neurodevelopmental disorders linked to aberrant protocadherin function, highlighting the significance of PCDHgA11 protein research in neurobiology and medicine.












