Analytical Data
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基因名
PCDHb9
- Application
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别名
PCDH3H; Protocadherin-3H
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y5E1
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表达区间
Gly27~Val232
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分子量
27kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PCDHb9 (Protocadherin beta 9) is a member of the protocadherin family, which is characterized by its role in mediating cell-cell interactions in the nervous system. These proteins are crucial for neuronal development and the formation of synapses, contributing to the complexity of neural networks. PCDHb9 is of particular interest due to its potential implications in neurodevelopmental disorders and neurological diseases. Research has shown that alterations in the expression or function of protocadherins may lead to abnormal neuronal connectivity, which is a hallmark of conditions such as autism spectrum disorder and schizophrenia. Consequently, understanding the structure and function of PCDHb9 through recombinant protein studies can provide insights into its biological role and mechanisms of action. Additionally, the development of PCDHb9 recombinant proteins allows for the exploration of its interactions with other proteins and its involvement in signaling pathways. By elucidating these interactions, researchers aim to uncover the molecular underpinnings of diseases linked to PCDHb9 dysregulation, paving the way for potential therapeutic strategies. Understanding the role of PCDHb9 in both health and disease contexts is critical for advancing our knowledge of brain function and developing novel approaches to treat neuropsychiatric disorders.
