Analytical Data
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基因名
PCDHb5
- Application
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种属
Rat
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
M0RC78
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表达区间
Glu39~Gln282
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分子量
34kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PCDHb5, a member of the protocadherin family, plays a crucial role in various cellular processes, including cell adhesion, signaling, and neural development. This protein is primarily expressed in the brain and is involved in the assembly and maintenance of neural circuits, indicating its significance in neurodevelopmental and neuropsychiatric disorders. Studies have shown that alterations in PCDHb5 expression or function may contribute to the pathogenesis of conditions such as schizophrenia, autism spectrum disorders, and other mental health issues. As a result, researchers are keenly interested in understanding the molecular mechanisms of PCDHb5, its interactions with other proteins, and its overall impact on neuronal stability and connectivity. Utilizing recombinant protein technology, scientists are able to produce PCDHb5 in vitro, allowing for a detailed analysis of its structural and functional properties. This research not only aims to elucidate the role of PCDHb5 in normal brain function but also seeks to identify potential therapeutic targets for treatment strategies in neurodevelopmental disorders. Overall, the study of PCDHb5 is pivotal for advancing our understanding of brain biology and developing interventions that could mitigate the effects of related neurological diseases.
