Analytical Data
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基因名
PCDHb3
- Application
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y5E6
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表达区间
Val35~Phe242
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分子量
30kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PCDHb3, a member of the protocadherin family, plays a crucial role in neuronal development and synaptic function. Recent studies have highlighted its significance in neural connectivity and cognitive processes, positioning PCDHb3 as a potential biomarker for neurodevelopmental disorders. Protocadherins, including PCDHb3, are known for their involvement in mediating cell-cell adhesion, which is essential for the formation and maintenance of neural networks. As research progresses, the therapeutic potential of recombinant PCDHb3 protein for neurodegenerative diseases and other neurological conditions is being explored. The ability to produce this protein in a recombinant form allows for detailed investigations into its structural and functional properties, paving the way for potential clinical applications. Understanding the mechanisms by which PCDHb3 influences cell signaling and interactions will enhance our knowledge of neural circuit formation and provide insights into therapeutic strategies for treating cognitive impairments associated with various neurological disorders.
