Analytical Data
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Gene name
PCDHgA3
- Application
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y5H0
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Expression Region
Gln30~Pro325
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Molecular Weight
39kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PCDHgA3, or Protocadherin Gamma A3, is a member of the protocadherin gene family, which plays a crucial role in neural development and synaptic function. Research into PCDHgA3 has gained significance due to its potential involvement in various neurological disorders, including autism spectrum disorders and schizophrenia. This protein is known for its unique structure, featuring multiple extracellular cadherin-like domains that facilitate cell-cell adhesion in the brain. Understanding the molecular mechanisms of PCDHgA3 and its interactions with other neural proteins may offer insights into the complexities of neuronal connectivity and function. Recent studies have utilized recombinant protein technologies to produce PCDHgA3, enabling detailed investigations into its biochemical properties and cellular functions. These studies aim to delineate how PCDHgA3 contributes to synaptic stability and plasticity, ultimately enhancing our understanding of its role in neurodevelopmental processes and disease pathogenesis. By focusing on the characterization of this protein, researchers hope to identify potential therapeutic targets for the treatment of related neurological conditions. Overall, the research on PCDHgA3 emphasizes the importance of cadherin-related proteins in maintaining neural health and their potential implications for understanding and treating brain disorders.
