Analytical Data
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基因名
Annexin A5/ANXA5
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简介
The annexin A5 (ANXA5) protein acts as an anticoagulant, indirectly inhibiting the thromboplastin-specific complex, which is critical in the coagulation cascade. As a monomer, ANXA5 plays a key role in regulating the coagulation pathway, affecting the delicate balance between pro- and anti-coagulant factors. Annexin A5/ANXA5 Protein, Mouse (His, Myc) is the recombinant mouse-derived Annexin A5/ANXA5 protein, expressed by E. coli , with N-10*His, C-Myc labeled tag.
- Application
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别名
ANXA5; Annexin A5
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种属
Mouse
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表达系统
E. coli
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标签
N-10*His;C-Myc
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
P48036
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表达区间
A2-D319
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蛋白长度
Full Length of Mature Protein
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分子量
38-41 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Annexin A5 (ANXA5) is a member of the annexin family of proteins, which are known for their ability to bind to phospholipids in a calcium-dependent manner. This protein plays a crucial role in various cellular processes, including apoptosis, cell migration, and membrane repair. The study of recombinant ANXA5 has garnered significant interest due to its potential applications in both basic research and clinical settings. In cellular contexts, ANXA5 is often implicated in the prevention of apoptosis and the modulation of inflammatory responses, making it a valuable target for therapeutic interventions in diseases such as cancer, cardiovascular disorders, and neurodegenerative conditions. The generation of recombinant ANXA5 allows researchers to investigate its biochemical properties, functional mechanisms, and interactions with other cellular components in detail. Furthermore, the use of recombinant protein technology has facilitated the production of modified forms of ANXA5, enhancing its properties for use in diagnostics and therapeutics. With ongoing research, ANXA5 continues to emerge as a promising biomarker and target for novel therapeutic strategies, underscoring the need for a deeper understanding of its biological functions and the development of effective applications in medicine.
