Cat: IPD-X38787

Recombinant Human TR4 Protein,His

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Analytical Data

  • 基因名

    TR4

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    NR2C2; TAK1; TR2R1; hTAK1; Nuclear Receptor Subfamily 2,Group C,Member 2; Orphan nuclear receptor TAK1

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P49116

  • 表达区间

    Leu371~Leu596

  • 分子量

    29kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

TR4 (Testicular Receptor 4) is a member of the nuclear receptor superfamily that plays crucial roles in various physiological processes, including reproductive development, metabolism, and cellular differentiation. Research on TR4 has gained momentum in recent years due to its potential implications in health and disease. The receptor regulates gene expression by binding to specific DNA sequences, influencing the transcription of target genes involved in metabolic pathways and hormonal responses. Dysregulation of TR4 has been linked to various conditions, including obesity, diabetes, and certain cancers, making it a target for therapeutic intervention. Further, TR4 is involved in processes such as spermatogenesis and immune responses, highlighting its multifaceted roles in both male and female biology. Understanding the structure-function relationship of TR4 and its interactions with co-regulators through recombinant protein studies is essential for elucidating its mechanisms of action. The development of recombinant TR4 proteins provides a valuable tool for investigating its signaling pathways and may facilitate the discovery of novel drugs targeting TR4-related pathways, ultimately offering new strategies in managing diseases associated with TR4 dysregulation. As research continues, the elucidation of TR4’s roles in various biological processes may contribute to innovative therapeutic approaches in both endocrinology and oncology.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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