Analytical Data
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基因名
RARg
- Application
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别名
NR1B3; RARC; Nuclear receptor subfamily 1 group B member 3
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P13631
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表达区间
Asp178~Glu423
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分子量
23kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RARγ (Retinoic Acid Receptor Gamma) is a member of the nuclear receptor superfamily that plays a crucial role in various biological processes, including development, immune function, and metabolism. Its activation by retinoic acid, a derivative of vitamin A, regulates gene expression involved in cell differentiation and proliferation. Dysregulation of RARγ has been implicated in several pathological conditions, including cancer and autoimmune diseases. Research into RARγ recombinant proteins has gained traction due to their potential therapeutic applications. Scientists have been exploring RARγ's structural and functional properties to understand its signaling pathways better and identify small molecules that can modulate its activity. The development of RARγ recombinant proteins allows for detailed studies of its interactions with ligands and co-regulators, contributing to a deeper understanding of its biological functions and the molecular mechanisms underlying related diseases. Furthermore, RARγ has emerged as a promising drug target, as compounds that can enhance or inhibit its activity could lead to novel treatments for conditions like acute promyelocytic leukemia (APL) and other disorders linked to retinoic acid signaling. Thus, the ongoing research on RARγ recombinant proteins is essential for unraveling its complex role in physiological and pathological contexts, paving the way for innovative therapeutic strategies.
