Analytical Data
-
基因名
PPAP2B
- Application
-
别名
Dri42; LPP3; PAP-2b; PAP2-b; PAP2-beta; VCIP; Lipid phosphate phosphohydrolase 3; Vascular endothelial growth factor and type I collagen-inducible protein
-
种属
Human
-
表达系统
E. coli
-
标签
N-His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
O14495
-
表达区间
Ser57~Ser194
-
分子量
19.3kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PPAP2B, also known as Phosphatidate Phosphatase 2B, is a crucial enzyme involved in lipid metabolism and cellular signaling processes. It plays a significant role in regulating levels of lysophosphatidic acid (LPA) and phosphatidic acid (PA), both of which are essential lipid mediators in cellular functions, including proliferation, survival, and differentiation. Dysregulation of PPAP2B is linked to various pathological conditions, including cancer, cardiovascular diseases, and metabolic disorders. Given its importance, researchers have focused on investigating the structure and function of PPAP2B through recombinant protein expression systems. These studies aim to provide insights into the enzyme's biochemical properties, optimal activity conditions, and potential regulatory mechanisms. Moreover, utilizing recombinant PPAP2B allows for detailed analyses of its interactions with cellular substrates and signaling pathways, which can enhance the understanding of its roles in health and disease. The ongoing research on PPAP2B is expected to pave the way for the development of targeted therapeutic strategies that can modulate its activity, offering new avenues for treating diseases associated with its dysregulation.
