Analytical Data
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Gene name
PPFIA1
- Application
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Alternative Names
LIP.1; LIP1; LIPRIN; Liprin-Alpha 1; LAR-interacting protein 1; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13136
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Expression Region
Met1~Ala250
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Molecular Weight
36kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PPFIA1, or Protein Phosphatase 1 Interacting Protein A1, is a member of the PPFIA family, known for its role in modulating protein phosphatase 1 (PP1) activity. Research into PPFIA1 has garnered interest due to its potential involvement in various cellular processes, including cell signaling, cytoskeletal organization, and neuronal function. Disruptions in PP1 regulation, facilitated by PPFIA1 interactions, have been implicated in several pathological conditions, including cancer and neurodegenerative diseases. As a scaffold protein, PPFIA1 is thought to orchestrate the assembly of protein complexes, thus influencing signal transduction pathways and cellular responses. Understanding the functional dynamics of PPFIA1 and its binding partners may reveal novel therapeutic targets and biomarkers for disease. Recent advances in recombinant protein technology have enabled the production of PPFIA1 for structural and functional studies, facilitating deeper insights into its role in cellular physiology and pathology. In light of its significance in modulating PP1 activity and involvement in critical cellular functions, PPFIA1 represents a key focus in the research community, particularly in the pursuit of delineating the molecular mechanisms underlying various diseases.
