Analytical Data
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基因名
STX1A
- Application
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别名
STX-1A; HPC-1; STX1; P35-1; Neuron-specific antigen HPC-1
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q16623
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表达区间
Met1~Val255
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分子量
33kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
STX1A, or Syntaxin 1A, is a pivotal protein involved in the process of synaptic vesicle fusion and neurotransmitter release in neurons. As a member of the Soluble N-ethylmaleimide-sensitive factor Attachment protein Receptor (SNARE) family, STX1A interacts with other SNARE proteins, such as SNAP-25 and VAMP, to form a functional membrane fusion complex crucial for effective synaptic transmission. Research has highlighted its role in various neurological processes and its implications in neurodegenerative diseases and synaptic disorders. Given the significance of synaptic signaling in the central nervous system, the study of STX1A and its recombinant protein form has garnered considerable attention. Researchers aim to elucidate its structural and functional properties, explore its interactions with other proteins, and understand its role in pathophysiological conditions. Moreover, STX1A's potential as a therapeutic target in treating neurological disorders underpins the necessity for advanced studies in this area. Recombinant STX1A proteins are utilized in assays to investigate protein interactions, vesicle trafficking dynamics, and the modulation of synaptic efficacy. Understanding STX1A at the molecular level could pave the way for novel interventions in treating synaptic dysfunctions, enhancing our ability to combat various cognitive and sensory impairments associated with neurological diseases. Overall, STX1A represents a critical area of research within molecular neuroscience, linking fundamental cellular mechanisms with clinical applications.
