Analytical Data
-
Gene name
SCG5
- Application
-
Alternative Names
SCGV; P7B2; SGNE1; SgV; 7B2 Protein; Neuroendocrine protein 7B2; Prohormone Convertase Chaperone; Pituitary polypeptide; Secretory granule endocrine protein I
-
Species
Human
-
Source
E. coli
-
Tag
N-His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P05408
-
Expression Region
Tyr27~Glu212
-
Molecular Weight
25kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SCG5, or Secretogranin V, is a member of the granin family of proteins, primarily expressed in neuroendocrine tissues. Its role in the biogenesis and function of neuroendocrine secretory vesicles has garnered significant interest, as it is involved in the regulation of peptide hormone storage and release. Research has shown that SCG5 may be implicated in various physiological processes, including neurotransmitter release and peptide hormone secretion, making it a potential biomarker for neuroendocrine tumors and related disorders. In recent studies, recombinant SCG5 protein has been produced to investigate its structure-function relationships and to explore its interactions with other proteins in the secretory pathway. Understanding SCG5's molecular mechanisms is crucial for elucidating its contributions to neuroendocrine physiology and its potential roles in pathological conditions. By producing and characterizing recombinant SCG5, researchers aim to provide insights that could lead to novel therapeutic strategies for diseases involving dysregulated neuroendocrine functions.
