Cat: IPD-X38609

Recombinant Human TSPAN3 Protein,His

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Analytical Data

  • 基因名

    TSPAN3

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    TM4-A; TM4A; TM4SF8; TSPAN3; Transmembrane 4 Superfamily Member 8

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O60637

  • 表达区间

    Tyr107~Ile213

  • 分子量

    20kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

TSPAN3, or Tetraspanin 3, is a member of the tetraspanin family of proteins that play critical roles in various cellular processes, including cell adhesion, migration, and signal transduction. Research on TSPAN3 has garnered significant interest due to its potential involvement in cancer metastasis and immune responses. Tetraspanins are known to facilitate the formation of specialized membrane microdomains, or "tetraspanin-enriched microdomains" (TEMs), which serve as platforms for the clustering of different receptors and adhesion molecules. Elevated expression levels of TSPAN3 have been associated with several cancers, suggesting that it may function as an oncogenic factor by promoting invasive behaviors of tumor cells. Furthermore, studies have indicated that TSPAN3 may influence immune cell activation and differentiation, thereby impacting immune responses. Understanding the functional mechanisms and interactions of TSPAN3 at the molecular level could provide insights into its role in tumor progression and the immune system. Consequently, recombinant TSPAN3 protein is often used in laboratory settings to explore its structural properties, binding partners, and functional implications in health and disease. Characterizing TSPAN3's role in cellular signaling and its contribution to pathological conditions may pave the way for novel therapeutic strategies targeting this protein, potentially leading to improved treatment options for cancer and immune-related disorders.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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