Analytical Data
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基因名
COMMD8
- Application
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种属
Human
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表达系统
E. coli
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标签
N-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
AAH19826
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表达区间
M1-K183
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氨基酸序列
MEPEEGTPLWRLQKLPAELGPQLLHKIIDGICGRAYPVYQDYHTVWESEEWMHVLEDIAKFFKAIVGKNLPDEEIFQQLNQLNSLHQETIMKCVKSRKDEIKQALSREIVAISSAQLQDFDWQVKLLLSSDKIAALRMPLLSLHLDVKENGEVKPYSIEMSREELQNLIQSLEAANKVVLQLK
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蛋白长度
Full Length
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分子量
23 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
COMMD8 (Copper Metabolism MURR1 Domain 8) is a member of the COMMD protein family, which is implicated in various cellular processes, including copper homeostasis, protein stability, and cellular signaling. The significance of COMMD8 has emerged in the context of its potential role in the regulation of gene expression and innate immunity. Recent studies have suggested that COMMD8 may participate in the modulation of inflammatory responses, making it a candidate for further exploration in diseases associated with dysregulated inflammation. The interest in COMMD8 has also been fueled by its interactions with other proteins and its involvement in pathways linked to cellular stress and apoptosis. Given its diverse roles, the development and characterization of recombinant COMMD8 protein offer valuable insights into its functionality and potential applications in therapeutic contexts. Recombinant protein production allows for the study of COMMD8's structural and biochemical properties, aiding in the elucidation of its mechanisms of action. Understanding these aspects may pave the way for innovative strategies aimed at targeting COMMD8-related pathways in various diseases, including autoimmune disorders and cancers. Thus, research on COMMD8 recombinant protein is pivotal in shedding light on its biological significance and therapeutic potential.












