Analytical Data
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基因名
NOR1
- Application
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别名
NR4A3; NR4-A3; CHN; TEC; CSMF; MINOR; NOR1; Nuclear Receptor Subfamily 4,Group A,Member 3; Mitogen-induced nuclear orphan receptor; Nuclear hormone receptor NOR-1
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种属
Rat
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P51179
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表达区间
Glu29~Pro145
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分子量
17kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NOR1, or nuclear receptor subfamily 4 group A member 1, is a member of the nuclear receptor superfamily and plays critical roles in various physiological processes, including metabolism, cardiovascular function, and reproductive health. As a transcription factor, NOR1 regulates the expression of genes involved in these processes by responding to various signaling pathways, including those activated by hormones and nutrient availability. Its significance has been underscored by studies linking NOR1 dysregulation to metabolic disorders, such as obesity and type 2 diabetes, as well as cardiovascular diseases. Recent investigations into the functional properties of recombinant NOR1 have focused on its ligand-binding capabilities and transcriptional activity, identifying potential therapeutic targets for intervention in related pathologies. By generating and characterizing recombinant NOR1 protein, researchers aim to unravel its intricate mechanisms of action and evaluate its potential as a drug target, especially in metabolic and cardiovascular diseases. Understanding NOR1's role in gene regulation and cellular signaling not only provides insight into its physiological importance but also opens avenues for the development of novel therapeutic strategies that could mitigate the impact of diseases associated with NOR1 malfunction. This research is vital in elucidating how NOR1 contributes to health and disease, ultimately paving the way for innovative treatments that harness its biological functions.












