Cat: IPD-X40945

Recombinant Human ANX1 Protein ,His

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Analytical Data

  • Gene name

    ANX1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Annexin IAnnexin-1Calpactin IICalpactin-2;Chromobindin-9Lipocortin IPhospholipase A2 inhibitory proteinp35

  • Species

    Human

  • Source

    E. coli

  • Tag

    N- His

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P04083

  • Expression Region

    5-346aa

  • Molecular Weight

    42.3 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ANX1, or Annexin A1, is a member of the annexin family of proteins, characterized by their ability to bind phospholipids in a calcium-dependent manner. It plays a crucial role in various physiological processes, including inflammation, cell signaling, and apoptosis. Due to its involvement in these essential cellular functions, ANX1 has garnered significant interest in biomedical research. Studies have indicated that ANX1 may exert anti-inflammatory effects and is implicated in the resolution of inflammation, making it a potential therapeutic target for inflammatory diseases. The recombinant form of ANX1 has been developed to facilitate detailed studies on its structure-function relationships and its interactions with cellular membranes, as well as to explore its potential therapeutic applications. Additionally, the recombinant protein serves as a valuable tool in understanding the molecular mechanisms of diseases where ANX1 is dysregulated. Recent research efforts focus on elucidating the pathways influenced by ANX1 and identifying its role in various pathological conditions, highlighting its significance in translational medicine. Overall, the study of ANX1 recombinant protein holds promise for advancing our understanding of its biological roles and potential therapeutic interventions.

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