Analytical Data
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基因名
CADPS
- Application
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别名
CAPS; CAPS1; Calcium-dependent activator protein for secretion 1
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9ULU8
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表达区间
Val1186~Asp1352
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分子量
53kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CADPS (Ca2+-dependent activator protein for secretion) is a crucial protein involved in neurotransmitter release and hormone secretion, playing a significant role in calcium signaling pathways. Understanding CADPS has garnered attention due to its implications in various neurological disorders and endocrine dysfunctions. Recent studies have indicated that CADPS interacts with SNARE proteins, facilitating the fusion of synaptic vesicles with the plasma membrane in response to calcium influx. The ability to produce and study recombinant CADPS proteins is vital for dissecting its molecular mechanisms and understanding how alterations in its function may contribute to pathophysiological conditions. Research on CADPS represents a promising avenue for developing therapeutic strategies aimed at restoring normal secretory processes in affected cells. Moreover, elucidating the structural and functional characteristics of CADPS could provide insights into potential drug targets for treating related diseases, fueling ongoing efforts in molecular biology and pharmacology.
