Analytical Data
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基因名
PTDSS1
- Application
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别名
Serine-exchange enzyme I
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种属
Human
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P48651
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表达区间
1-35aa
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分子量
31.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PTDSS1 (Phosphatidylserine Synthase 1) is an essential enzyme involved in the biosynthesis of phosphatidylserine, a crucial phospholipid component of cell membranes that plays significant roles in cell signaling, apoptosis, and membrane dynamics. Recent studies have highlighted the importance of PTDSS1 in various biological processes, including neurodevelopment, cellular stress responses, and immune regulation. Dysregulation of PTDSS1 has been associated with numerous pathologies, such as neurodegenerative diseases, cancer, and metabolic disorders. Given its vital role in maintaining cellular function and integrity, PTDSS1 has emerged as a promising therapeutic target. Researchers are focusing on the recombinant expression of PTDSS1 to better understand its structure and function, facilitating the development of novel inhibitors or modulators that could have significant implications in treating diseases linked to phosphatidylserine metabolism. The study of PTDSS1 also opens avenues for exploring its potential in enhancing therapeutic strategies for conditions where phospholipid metabolism is disrupted. Through the use of advanced protein engineering techniques, scientists aim to produce functional PTDSS1 variants that can be used in biochemical assays and drug design, thereby contributing to a deeper understanding of its biological roles and therapeutic potential.
