Analytical Data
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Gene name
FABP5
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简介
FABP5, also known as E-FABP, acts as an intracellular carrier of long-chain fatty acids and related lipids and regulates ligand metabolism.In addition to cytoplasmic transport, it selectively transports fatty acids to the nucleus, activates nuclear receptors, and delivers retinoic acid to promote proliferation.FABP5 Protein, Mouse (His) is the recombinant mouse-derived FABP5 protein, expressed by E.coli , with N-6*His labeled tag.
- Application
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Species
Mouse
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Source
E. coli
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Tag
N-6*His
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Purity
Greater than 95% as determined by SDS-PAGE.
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Uniprot
Q05816
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Expression Region
M1-Q135
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Protein Length
Full Length
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Molecular Weight
16 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Fatty acid-binding protein 5 (FABP5) is a member of the fatty acid-binding protein family, which plays a crucial role in the intracellular transport and metabolism of fatty acids and other lipophilic substances. Over recent years, increasing evidence has linked FABP5 to various physiological processes, including lipid metabolism, insulin sensitivity, and inflammation. Dysregulation of FABP5 has been implicated in several metabolic disorders, such as obesity, type 2 diabetes, and cardiovascular diseases. Moreover, FABP5 is involved in the modulation of gene expression and signaling pathways, thereby influencing cell proliferation and differentiation. Given its significant role in metabolic regulation and disease pathogenesis, the study of recombinant FABP5 has garnered attention for its potential therapeutic applications. Researchers aim to explore the structural and functional characteristics of FABP5, which could lead to the development of novel strategies for treating metabolic disorders. By generating and analyzing recombinant FABP5 proteins, scientists can gain insights into the mechanisms by which FABP5 influences metabolic pathways, providing a basis for future drug design and interventions aimed at modulating its activity in disease contexts.
