Analytical Data
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Gene name
UQCR11
- Application
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Alternative Names
Complex III subunit 10Complex III subunit XIUbiquinol-cytochrome c reductase complex 6.4KDA protein
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O14957
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Expression Region
1-56aa
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Molecular Weight
33.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
UQCR11, also known as the Ubiquinol-cytochrome c reductase complex assembly factor, plays a crucial role in the function of the mitochondrial respiratory chain, specifically in the assembly of complex III. The study of UQCR11 is significant as mitochondrial dysfunction is implicated in various diseases, including neurodegenerative disorders, metabolic syndromes, and cancer. Understanding UQCR11's role in mitochondrial biogenesis and energy production can provide insights into the underlying mechanisms of these pathologies. Additionally, research has shown that UQCR11 is involved in the regulation of reactive oxygen species (ROS) production, which is pivotal in cellular signaling and stress responses. Moreover, exploring UQCR11’s interactions with other mitochondrial proteins and its potential as a therapeutic target could lead to novel strategies for treating mitochondrial-related diseases. Increased knowledge of UQCR11 not only enhances our comprehension of mitochondrial dynamics but also highlights its importance in maintaining cellular homeostasis. Given its functional relevance, UQCR11 represents a compelling target for future research aimed at elucidating mitochondrial function and its broader implications in human health.
