Analytical Data
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基因名
SYNCRIP
- Application
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别名
Glycine- and tyrosine-rich RNA-binding protein ;GRY-RBPNS1-associated protein 1Synaptotagmin-binding, Cytoplasmic domain RNA-interacting protein
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种属
Human
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O60506
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表达区间
2-191aa
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分子量
47.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SYNCRIP, a member of the synaptotagmin family, is an RNA-binding protein that plays a crucial role in regulating RNA metabolism, transport, and stability in various cellular contexts. Initially discovered for its involvement in synaptic functions, subsequent studies have revealed its diverse biological functions, including its role in neuronal development and synaptic plasticity. In addition to its neural implications, SYNCRIP has been shown to interact with a variety of RNA targets, influencing gene expression and cellular responses to stress. Given its pivotal roles, researchers are increasingly focused on understanding the molecular mechanisms by which SYNCRIP exerts its effects, particularly in the context of neurodegenerative diseases and other disorders where RNA metabolism is disrupted. Exploring these pathways could provide insights into potential therapeutic targets, emphasizing the importance of SYNCRIP in maintaining cellular homeostasis and its contributions to various pathophysiological conditions. Understanding SYNCRIP's interactions and functions could pave the way for novel therapeutic strategies in treating diseases associated with RNA dysregulation, highlighting its significance in both basic biology and clinical research.












