Analytical Data
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基因名
PRKCSH
- Application
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别名
80K-H protein;Glucosidase II subunit betaProtein kinase C substrate 60.1KDA protein heavy chain ;PKCSH
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种属
Human
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P14314
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表达区间
15-302aa
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分子量
59.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PRKCSH (Protein Kinase C Substrate 80K-H) is a significant protein involved in various cellular processes, including cell signaling and metabolism. Research into PRKCSH has gained importance due to its role in human health, particularly in conditions such as liver diseases and tumors. It has been identified as a key factor in the development of certain types of hereditary kidney diseases, where mutations in the PRKCSH gene lead to impaired cellular functions. These mutations are known to cause a variety of disorders, including autosomal dominant polycystic kidney disease. The protein itself interacts with multiple signaling pathways, underscoring its potential influence on both normal physiology and disease states. Given its pivotal roles, researchers are investigating PRKCSH to understand its structural biology, functional mechanisms, and therapeutic potential. The exploration of PRKCSH as a recombinant protein also opens avenues for developing targeted treatments, diagnostic tools, and better understanding of its interactions within the cell. Efforts are being made to elucidate its biological functions and pathways, which could ultimately lead to new interventions for diseases associated with its dysfunction. This makes PRKCSH a focal point for both basic research and translational studies in biomedical science. As a result, characterizing PRKCSH through recombinant technology could provide insights into its regulatory roles and facilitate the discovery of new clinical applications in treating related conditions. Overall, PRKCSH represents a crucial target in understanding disease mechanisms and developing novel therapeutic strategies.












