Analytical Data
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Gene name
PRKCSH
- Application
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Alternative Names
80K-H protein;Glucosidase II subunit betaProtein kinase C substrate 60.1KDA protein heavy chain ;PKCSH
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P14314
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Expression Region
15-302aa
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Molecular Weight
59.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PRKCSH (Protein Kinase C Substrate 80K-H) is a significant protein involved in various cellular processes, including cell signaling and metabolism. Research into PRKCSH has gained importance due to its role in human health, particularly in conditions such as liver diseases and tumors. It has been identified as a key factor in the development of certain types of hereditary kidney diseases, where mutations in the PRKCSH gene lead to impaired cellular functions. These mutations are known to cause a variety of disorders, including autosomal dominant polycystic kidney disease. The protein itself interacts with multiple signaling pathways, underscoring its potential influence on both normal physiology and disease states. Given its pivotal roles, researchers are investigating PRKCSH to understand its structural biology, functional mechanisms, and therapeutic potential. The exploration of PRKCSH as a recombinant protein also opens avenues for developing targeted treatments, diagnostic tools, and better understanding of its interactions within the cell. Efforts are being made to elucidate its biological functions and pathways, which could ultimately lead to new interventions for diseases associated with its dysfunction. This makes PRKCSH a focal point for both basic research and translational studies in biomedical science. As a result, characterizing PRKCSH through recombinant technology could provide insights into its regulatory roles and facilitate the discovery of new clinical applications in treating related conditions. Overall, PRKCSH represents a crucial target in understanding disease mechanisms and developing novel therapeutic strategies.
