Cat: IPD-X26529

Recombinant Human Annexin A5/ANXA5 Protein,His

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Analytical Data

  • Gene name

    Annexin A5/ANXA5

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ANX5; ENX2; PP4; PAP-I; CBP-I; Anchorin CII; Calphobindin I; Endonexin II; Lipocortin V; Placental anticoagulant protein 4; Thromboplastin inhibitor; Vascular anticoagulant-alpha

  • Species

    Human

  • Source

    E. coli

  • Tag

    N-His

  • Purity

    Greater than 95% as determined by SDS-PAGE.

  • Uniprot

    P08758

  • Expression Region

    Met1~Asp320

  • Molecular Weight

    37kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Annexin A5 (ANXA5) is a member of the annexin family of proteins, which are known for their ability to bind to phospholipids in a calcium-dependent manner. This protein plays a crucial role in various cellular processes, including apoptosis, cell migration, and membrane repair. The study of recombinant ANXA5 has garnered significant interest due to its potential applications in both basic research and clinical settings. In cellular contexts, ANXA5 is often implicated in the prevention of apoptosis and the modulation of inflammatory responses, making it a valuable target for therapeutic interventions in diseases such as cancer, cardiovascular disorders, and neurodegenerative conditions. The generation of recombinant ANXA5 allows researchers to investigate its biochemical properties, functional mechanisms, and interactions with other cellular components in detail. Furthermore, the use of recombinant protein technology has facilitated the production of modified forms of ANXA5, enhancing its properties for use in diagnostics and therapeutics. With ongoing research, ANXA5 continues to emerge as a promising biomarker and target for novel therapeutic strategies, underscoring the need for a deeper understanding of its biological functions and the development of effective applications in medicine.

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