Cat: IPD-X40815

Recombinant Human MRPS16 Protein ,GST

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Analytical Data

  • Gene name

    MRPS16

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    28S ribosomal protein S16; 28S ribosomal protein S16 mitochondrial; CGI-132; COXPD2; mitochondrial; Mitochondrial ribosomal protein S16; MRP-S16; mrps16; RPMS16; RT16_HUMAN; S16mt

  • Species

    Human

  • Source

    E. coli

  • Tag

    N- GST

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9Y3D3

  • Expression Region

    1-137aa

  • Molecular Weight

    38.5 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

MRPS16 (Mitochondrial Ribosomal Protein S16) is a crucial component of the mitochondrial ribosome, playing a significant role in mitochondrial protein synthesis. Research has shown that MRPS16 is involved in the assembly and function of mitochondrial ribosomes, which are essential for the production of proteins encoded by mitochondrial DNA. Deficiencies or mutations in MRPS16 can lead to various mitochondrial diseases, characterized by impaired energy metabolism and a range of disorders affecting multiple organ systems. Furthermore, studies have indicated that MRPS16 may have implications in cell growth, apoptosis, and the overall maintenance of mitochondrial integrity. Given the essential functions of MRPS16 in mitochondrial biology, understanding its structure, function, and interactions with other mitochondrial components is vital for elucidating the mechanisms underlying mitochondrial diseases. This research can potentially lead to novel therapeutic strategies aimed at targeting mitochondrial dysfunction, making MRPS16 a significant focus in the field of mitochondrial research and related therapeutic development.

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