Analytical Data
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Gene name
GnRHR
- Application
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Alternative Names
GnRH-R; LRHR; Luteinizing Hormone Releasing Hormone Receptor
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Species
Rat
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P30969
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Expression Region
Lys232~Thr280
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Molecular Weight
40kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Gonadotropin-releasing hormone receptor (GnRHR) plays a pivotal role in the regulation of the reproductive system by mediating the release of gonadotropins from the pituitary gland. Understanding the structure and function of GnRHR is essential for elucidating its role in reproductive endocrinology and for developing therapeutic strategies for related disorders, such as infertility and hormone-dependent cancers. Research on GnRHR recombinant proteins has emerged as a critical area of focus, as these proteins can be used to develop antibodies, study receptor signaling pathways, and explore ligand-receptor interactions. The ability to produce GnRHR in a recombinant form allows for the detailed characterization of its biochemical properties and interactions, paving the way for advancements in treatments targeting dysregulation of the gonadotropic axis. Furthermore, given the complexity of signaling and receptor activation in the endocrine system, investigating GnRHR through reconstitution studies in heterologous systems can provide insights into its functional dynamics and potential pharmaceutical applications. Overall, GnRHR recombinant protein research contributes significantly to our understanding of reproductive physiology and holds promise for innovations in the management of reproductive health issues.
