Analytical Data
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基因名
TMEM175
- Application
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别名
Endosomal/lysosomal proton channel TMEM175; Potassium channel TMEM175; Transmembrane protein 175; hTMEM175; TMEM175; Homo sapiens; Human; Ion channel; Potassium channel
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种属
Human
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表达系统
HEK293
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标签
Tag Free
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BSA9-1
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表达区间
M1-C504
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蛋白长度
Full Length of Isoform-1
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分子量
56.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TMEM175 is a member of the transmembrane protein family that has garnered attention due to its potential role in regulating ion homeostasis and cellular functions. Recent studies have suggested that TMEM175 may be involved in lysosomal ion transport, particularly potassium ions, which are crucial for maintaining cellular pH and overall cellular health. Its association with various neurological disorders, including neurodegenerative diseases, has further motivated research into its structure and function. Recombinant TMEM175 protein is largely studied to elucidate its mechanism in cellular pathways and its implications in disease processes. Understanding the properties of TMEM175 can provide insights not only into fundamental biological processes but also pave the way for therapeutic interventions targeting ion transport dysregulation associated with specific diseases. As researchers continue to explore the functional aspects of TMEM175, the discovery of its potential as a biomarker or therapeutic target remains a tantalizing area of investigation in the field of cellular biology and medicine.
