Analytical Data
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基因名
ADCY2
- Application
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别名
HBAC2; ATP pyrophosphate-lyase 2; Adenylate cyclase type II
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q08462
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表达区间
Ala294~Thr525
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分子量
31kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ADCY2 (Adenylate Cyclase 2) is a crucial enzyme that plays a significant role in cellular signaling by converting ATP to cyclic AMP (cAMP), a vital second messenger involved in various physiological processes, including neurotransmission, hormone signaling, and cardiac function. The importance of ADCY2 comes from its distinct regulatory mechanisms and tissue-specific expression patterns, which suggest that it may have unique roles in different biological contexts. Mutations or dysregulation of ADCY2 have been linked to various pathological conditions, including heart diseases, neurological disorders, and metabolic syndromes, highlighting its potential as a therapeutic target. Research into ADCY2 recombinant proteins aims to elucidate its structure-function relationship, enabling a better understanding of its catalytic mechanisms and how it interacts with various regulatory proteins. Moreover, investigating ADCY2 through recombinant protein studies can pave the way for drug discovery, particularly in developing specific inhibitors or activators that could modulate its activity in disease states. As such, ADCY2 represents a compelling subject for both fundamental biological research and clinical applications, driving interest in its detailed study at the molecular level.
