Analytical Data
-
Gene name
ADCY2
- Application
-
Alternative Names
HBAC2; ATP pyrophosphate-lyase 2; Adenylate cyclase type II
-
Species
Human
-
Source
E. coli
-
Tag
N-His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q08462
-
Expression Region
Ala294~Thr525
-
Molecular Weight
31kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ADCY2 (Adenylate Cyclase 2) is a crucial enzyme that plays a significant role in cellular signaling by converting ATP to cyclic AMP (cAMP), a vital second messenger involved in various physiological processes, including neurotransmission, hormone signaling, and cardiac function. The importance of ADCY2 comes from its distinct regulatory mechanisms and tissue-specific expression patterns, which suggest that it may have unique roles in different biological contexts. Mutations or dysregulation of ADCY2 have been linked to various pathological conditions, including heart diseases, neurological disorders, and metabolic syndromes, highlighting its potential as a therapeutic target. Research into ADCY2 recombinant proteins aims to elucidate its structure-function relationship, enabling a better understanding of its catalytic mechanisms and how it interacts with various regulatory proteins. Moreover, investigating ADCY2 through recombinant protein studies can pave the way for drug discovery, particularly in developing specific inhibitors or activators that could modulate its activity in disease states. As such, ADCY2 represents a compelling subject for both fundamental biological research and clinical applications, driving interest in its detailed study at the molecular level.
