Cat: IPD-X38366

Recombinant Rat NGAL Protein,His

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Analytical Data

  • 基因名

    NGAL

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Lipocalin-2; LCN2; p25; Lipocalin 2; Oncogene 24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; Siderocalin LCN2

  • 种属

    Rat

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P30152

  • 表达区间

    Gln21~Asn198

  • 分子量

    26kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

NGAL (Neutrophil Gelatinase-Associated Lipocalin) is a small, secreted protein that plays a significant role in various physiological and pathological processes, particularly in the context of acute kidney injury (AKI) and inflammation. As a component of the lipocalin family, NGAL binds to small hydrophobic molecules and is involved in the transport of these molecules, which contributes to its diverse biological functions. Elevated levels of NGAL in urine and serum have been identified as promising early biomarkers for AKI, facilitating early diagnosis and intervention. Research into recombinant NGAL (rNGAL) focuses on its potential therapeutic applications, as well as its mechanistic role in kidney protection and repair. The production of rNGAL using recombinant DNA technology allows for the study of its structure, function, and interaction with other proteins, making it a valuable tool for investigating renal pathology. Moreover, the potential use of rNGAL as a biomarker or therapeutic agent has spurred interest in understanding its modulatory effects on inflammation and fibrosis within the kidneys. By delineating the role of NGAL in renal physiology and disease, researchers aim to develop targeted strategies for preventing or treating AKI and improving patient outcomes.

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Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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