Analytical Data
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Gene name
Trx-2
- Application
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Alternative Names
Short name: DmTrx-2
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Species
Drosophila melanogaster
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9V429
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Expression Region
1-114aa
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Molecular Weight
28.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TRX-2, or Thioredoxin-2, is a member of the thioredoxin family of proteins renowned for their role in maintaining redox balance within cells. This protein is localized primarily in the mitochondria and plays a critical role in cellular protection against oxidative stress, which is implicated in various diseases, including neurodegenerative disorders, cancer, and cardiovascular diseases. Given its significant function in regulating oxidative stress responses and maintaining mitochondrial integrity, TRX-2 has garnered attention in biomedical research. Understanding the mechanisms by which TRX-2 operates may provide insights into its potential therapeutic applications, particularly in conditions characterized by elevated oxidative stress. The study of TRX-2 also extends to its interactions with other cellular pathways and its involvement in apoptosis, as well as its potential as a biomarker for disease progression. Furthermore, advancements in recombinant protein technology have enabled the production of TRX-2 for experimental studies, thereby facilitating the exploration of its biological functions and pathways. Researchers aim to unravel the multifaceted roles of TRX-2 within the cellular context, making it a focal point for therapeutic strategies aimed at mitigating oxidative damage and improving cellular health. This research holds promise for the development of novel interventions that could enhance the resilience of cells against oxidative stress-related conditions, ultimately contributing to strategies for disease prevention and management.
