Analytical Data
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基因名
PYK2
- Application
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别名
PKB; CADTK; CAKB; FADK2; FAK2; PTK; PTK2b; RAFTK; Calcium-dependent tyrosine kinase; Cell adhesion kinase beta; Focal adhesion kinase 2; Proline-rich tyrosine kinase 2
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种属
Mouse
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9QVP9
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表达区间
Ile704~Gly941
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分子量
57kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Pyk2 (proline-rich tyrosine kinase 2) is a non-receptor tyrosine kinase that plays a crucial role in various cellular processes, including cell adhesion, migration, and signaling. Investigating Pyk2 and its signaling pathways has garnered significant attention in recent years due to its essential functions in both normal cellular physiology and pathological conditions, such as cancer metastasis and neurodegenerative diseases. The protein is activated by various stimuli, including integrin engagement and growth factor receptor activation, leading to autophosphorylation and the recruitment of downstream signaling molecules. Recombinant Pyk2 protein is used extensively in biochemical and biophysical studies to elucidate its structure-function relationships, enzymatic activity, and interaction with other proteins. Understanding these mechanisms is vital for developing therapeutic strategies targeting Pyk2-related pathways. Moreover, the potential of Pyk2 as a biomarker for certain diseases highlights its importance in clinical research. Overall, the study of recombinant Pyk2 protein contributes significantly to our understanding of cellular signaling networks and their implications in health and disease.
