Analytical Data
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Gene name
GPR75
- Application
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Alternative Names
Probable G-protein coupled receptor 75; GPR75; Homo sapiens; Human; G-protein coupled receptor; Receptor; Transducer
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Species
Human
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Source
HEK293
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Tag
N-Flag;C-10*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O95800
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Expression Region
M1-R236, S307-G395
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Protein Length
Partial
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Molecular Weight
49 kDa, based on SDS-PAGE under reducing conditions
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPR75, a member of the G protein-coupled receptors (GPCRs) family, is implicated in various physiological processes, including metabolism and the regulation of appetite. It is predominantly expressed in the central nervous system, hinting at its potential role in neuroendocrine functions. Recent studies have suggested that GPR75 may be involved in the signaling pathways related to obesity and metabolic disorders, making it a potential target for therapeutic interventions. However, the exact mechanisms of action and potential ligands for GPR75 remain poorly understood, underscoring the necessity for detailed investigations. The recombinant expression of GPR75 in appropriate systems allows for a better understanding of its structural and functional properties, ultimately facilitating the discovery of small molecules or peptides that can modulate its activity. This research not only enhances our comprehension of GPR75's biological functions but also opens pathways for developing novel strategies in combating metabolic diseases. As such, the study of GPR75 recombinant protein is a promising area of research with significant implications for health and disease management.
