Analytical Data
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Gene name
ITGa3
- Application
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Alternative Names
CD49c; CD49-C; ITG-A3; GAP-B3; GAPB3; MSK18; VCA-2; VL3A; VLA3a; FRP-2; Galactoprotein B3; Alpha 3 Subunit Of VLA-3 Receptor; CD49 antigen-like family member C
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q62470
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Expression Region
Phe33~Glu236
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Molecular Weight
27kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ITGa3 (integrin alpha 3) is a critical cell surface receptor that plays a significant role in various cellular processes, including cell adhesion, migration, and signaling pathways. It is part of the integrin family, which facilitates interactions between cells and the extracellular matrix, thereby influencing tissue development and repair. Research on ITGa3 is particularly relevant in the context of cancer biology, as its expression is often altered in malignant cells, contributing to tumor progression and metastasis. Additionally, ITGa3 is involved in immune responses and may be implicated in autoimmune diseases. Understanding the structure and function of ITGa3 through recombinant protein studies can provide insights into its role in disease mechanisms and offer potential therapeutic targets. Recent advances in biotechnology enable the production of recombinant ITGa3 proteins, enhancing our ability to study their properties and interactions. This research not only contributes to basic biological knowledge but also paves the way for developing novel diagnostics and treatments for diseases associated with integrin dysregulation.











