Analytical Data
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Gene name
RAB23
- Application
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Alternative Names
DKFZp781H0695; HSPC137; MGC8900; Rab 23; RAB family small GTP binding protein RAB 23; Rab23; RAB23; member RAS oncogene family; RAB23_HUMAN; Ras related protein Rab 23; Ras-related protein Rab-23
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9ULC3
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Expression Region
1-237aa
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Molecular Weight
53.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAB23 is a member of the RAB family of small GTPases, which play crucial roles in intracellular trafficking and signal transduction pathways. It is primarily involved in the regulation of membrane trafficking processes, especially in endosomal and lysosomal systems. Research has shown that RAB23 is implicated in various physiological and pathological conditions, including cancer progression, developmental disorders, and neurodegenerative diseases. Its function in regulating the movement of proteins and organelles within cells makes it a vital component for maintaining cellular homeostasis. In particular, mutations in the RAB23 gene have been linked to Greig cephalopolysyndactyly syndrome, a genetic condition characterized by developmental abnormalities. The study of RAB23 recombinant proteins has become increasingly important for understanding its biochemical properties, interactions with other cellular components, and its role in disease mechanisms. By producing and characterizing RAB23 in a recombinant form, researchers aim to elucidate the molecular pathways regulated by this GTPase and explore its potential as a therapeutic target. Furthermore, examining the functional aspects of RAB23 through its recombinant protein can provide insights into its role in cell signaling and transport processes, enabling a better understanding of its contribution to human health and disease. Overall, the study of RAB23 recombinant protein holds significant promise for advancing our knowledge of cellular dynamics and developing novel strategies for disease intervention.
