Analytical Data
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基因名
RAB23
- Application
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别名
DKFZp781H0695; HSPC137; MGC8900; Rab 23; RAB family small GTP binding protein RAB 23; Rab23; RAB23; member RAS oncogene family; RAB23_HUMAN; Ras related protein Rab 23; Ras-related protein Rab-23
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种属
Human
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9ULC3
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表达区间
1-237aa
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分子量
53.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RAB23 is a member of the RAB family of small GTPases, which play crucial roles in intracellular trafficking and signal transduction pathways. It is primarily involved in the regulation of membrane trafficking processes, especially in endosomal and lysosomal systems. Research has shown that RAB23 is implicated in various physiological and pathological conditions, including cancer progression, developmental disorders, and neurodegenerative diseases. Its function in regulating the movement of proteins and organelles within cells makes it a vital component for maintaining cellular homeostasis. In particular, mutations in the RAB23 gene have been linked to Greig cephalopolysyndactyly syndrome, a genetic condition characterized by developmental abnormalities. The study of RAB23 recombinant proteins has become increasingly important for understanding its biochemical properties, interactions with other cellular components, and its role in disease mechanisms. By producing and characterizing RAB23 in a recombinant form, researchers aim to elucidate the molecular pathways regulated by this GTPase and explore its potential as a therapeutic target. Furthermore, examining the functional aspects of RAB23 through its recombinant protein can provide insights into its role in cell signaling and transport processes, enabling a better understanding of its contribution to human health and disease. Overall, the study of RAB23 recombinant protein holds significant promise for advancing our knowledge of cellular dynamics and developing novel strategies for disease intervention.












