Cat: IPD-X38348

Recombinant Mouse GZMK Protein,His

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Analytical Data

  • 基因名

    GZMK

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    GZM-K; TRYP2; PRSS; Serine Protease,Granzyme 3; Tryptase II; Fragmentin-3; Granzyme-3; NK-tryptase-2

  • 种属

    Mouse

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O35205

  • 表达区间

    Gln44~Val227

  • 分子量

    24kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

GZMK, or granulocyte aminopeptidase M, is a member of the peptidase M family and plays a significant role in immune responses and inflammation. Recent studies have emphasized its potential implications in various diseases, particularly in cancer and autoimmune disorders. The protein is primarily expressed in activated T cells and plays a crucial role in regulating immune cell functions and mediating cellular interactions. Its involvement in the processing of peptides for major histocompatibility complex (MHC) class II presentation enhances our understanding of T cell activation and the adaptive immune system. Research into GZMK recombinant proteins has gained momentum due to their potential applications in immunotherapy and vaccine development. By elucidating the structure-function relationship and the underlying mechanisms of GZMK, scientists aim to leverage its unique properties to enhance anti-tumor responses and modulate immune tolerance. Furthermore, the production of recombinant GZMK proteins facilitates the exploration of their biochemical properties, opening avenues for therapeutic interventions. Understanding GZMK's functional dynamics could lead to innovative strategies for treating immune-related diseases and improving vaccine efficacy in the context of infectious diseases and cancer. As such, GZMK has emerged as a promising target in both basic and applied biomedical research, warranting further investigation into its role in health and disease.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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