Analytical Data
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Gene name
RMND5A
- Application
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Alternative Names
RMND5A; E3 ubiquitin-protein transferase RMND5A; EC 2.3.2.27; P44CTLH; Protein RMD5 homolog A
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Species
Human
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H871
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Expression Region
1-385aa
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Molecular Weight
59.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RMND5A, or "required for meiotic nuclear development 5A," is a gene that has garnered attention in recent years due to its crucial role in cellular processes, particularly in meiosis and nuclear development. Research shows that RMND5A is involved in the regulation of gene expression and protein synthesis, which is vital for reproductive biology. Variants in this gene have been associated with several disorders, including infertility and various developmental anomalies. Understanding the function of RMND5A and its protein product is essential for elucidating the underlying mechanisms of gametogenesis and associated pathologies. Recombinant RMND5A protein is increasingly being produced in laboratory settings to facilitate studies investigating its structure, function, and interactions with other cellular components. Characterizing RMND5A through recombinant technology will enhance our understanding of its role in biological processes and its potential implications in therapeutic biochemistry. Researchers are particularly interested in using this protein to explore its post-translational modifications, interaction partners, and specific functions in meiosis. This research could ultimately lead to novel insights into fertility treatments and the genetic basis of reproductive health issues. Overall, the study of RMND5A and its recombinant protein is a promising avenue in both basic and applied biological research, holding potential for advancements in reproductive medicine and gene therapy.
