Analytical Data
-
Gene name
HAUS4
- Application
-
Alternative Names
HAUS4; C14orf94HAUS augmin-like complex subunit 4
-
Species
Human
-
Source
E. coli
-
Tag
N- GST
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9H6D7
-
Expression Region
1-363aa
-
Molecular Weight
69.4 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HAUS4 is a crucial component of the HAUS (Human Augmin-like) complex, which plays a significant role in microtubule organization and the formation of the spindle apparatus during cell division. Research on HAUS4 has gained traction due to its critical involvement in ensuring proper chromosomal segregation, which is essential for maintaining genomic stability. Dysregulation of HAUS4 and its associated proteins has been linked to various cancers, highlighting its potential as a therapeutic target. Understanding the biochemical properties and regulatory mechanisms of HAUS4 is vital for elucidating its function in the cell cycle and its role in disease pathology. Furthermore, the study of HAUS4 enhances our understanding of the molecular machinery that governs cell division, offering insights into potential interventions in cancer treatment and other related disorders. The ongoing research aims to characterize HAUS4's interactions within the HAUS complex and its impact on microtubule dynamics, contributing to a broader comprehension of cellular processes and potential avenues for clinical applications.
