Analytical Data
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基因名
GNB1L
- Application
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别名
DGCRK3 WD repeat-containing protein 14 WD40 repeat-containing protein deleted in VCFS
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种属
Human
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BYB4
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表达区间
1-327aa
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分子量
62.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GNB1L (Guanine nucleotide-binding protein beta subunit-like) is a crucial protein involved in various signaling pathways that regulate cellular processes, including growth, differentiation, and apoptosis. Researchers have focused on GNB1L due to its potential implications in various diseases, particularly cancer, where aberrant signaling pathways contribute to tumorigenesis. Recent studies have highlighted its role in modulating G protein-coupled receptor (GPCR) signaling, which is essential for maintaining cellular homeostasis. The recombinant expression of GNB1L provides a valuable tool for investigating its biological functions and interactions with other proteins in signaling networks. By producing and characterizing GNB1L as a recombinant protein, scientists aim to enhance our understanding of its structural properties and functional mechanisms. This research may pave the way for novel therapeutic strategies targeting GNB1L-related pathways, potentially offering new avenues for the treatment of diseases linked to dysregulated GPCR signaling. Furthermore, understanding GNB1L's biochemical characteristics can facilitate the development of high-throughput screening assays to identify small molecules that can modulate its activity, contributing to drug discovery efforts. Overall, the study of GNB1L recombinant protein is significant for both fundamental biology and clinical applications, highlighting the importance of this protein in health and disease.












