Analytical Data
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Gene name
SOX18
- Application
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Alternative Names
HLTS; SRY-Box 18
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Species
Rat
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q4V7E4
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Expression Region
Lys153~Gly377
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Molecular Weight
31kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors, which play critical roles in various developmental processes, particularly in the regulation of gene expression during embryogenesis. Recent studies have highlighted SOX18's significant involvement in vascular development and lymphangiogenesis, which are crucial for proper tissue function and fluid homeostasis. Mutations in the SOX18 gene have been linked to human disorders, such as hypotrichosis with lymphedema and other congenital anomalies. The production of recombinant SOX18 protein facilitates in-depth studies of its structure, function, and interaction with other molecular players in developmental pathways. By utilizing techniques such as bacterial or eukaryotic expression systems, researchers can obtain large quantities of SOX18, enabling functional assays and structural analyses. Understanding SOX18's mechanisms of action may provide insights into developmental biology and pathologies associated with its dysregulation. Additionally, investigating the therapeutic potential of modulating SOX18 activity could lead to novel strategies for treating diseases related to vascular or lymphatic abnormalities. Overall, the study of SOX18 recombinant protein offers a promising avenue for elucidating its biological roles and therapeutic targeting in relevant medical conditions.
