Analytical Data
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Gene name
MUC17
- Application
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Alternative Names
MUC3; Mucin Cell Surface Associated; Small intestinal mucin-3
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q685J3
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Expression Region
Thr3773~Thr3998
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Molecular Weight
30kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MUC17 is a member of the mucin family of glycoproteins, which are characterized by their high glycosylation and large size, playing crucial roles in protective mucosal barriers in various tissues, particularly in the gastrointestinal tract. Research on MUC17 has garnered attention due to its involvement in various physiological and pathological processes, including inflammation and cancer progression. Specifically, MUC17 is expressed in epithelial cells, where it contributes to the formation of the protective mucous layer, thus playing a vital role in maintaining mucosal integrity. Its expression patterns have been observed to change in several diseases, including colorectal cancer, where it may facilitate tumor progression and metastasis. The interest in MUC17 as a therapeutic target has prompted studies aimed at understanding its structural and functional properties, which can aid in the development of diagnostic markers or potential therapeutic strategies. Recombinant MUC17 protein production has emerged as a vital tool in this research, enabling scientists to study its interactions with other molecules, assess its role in cell signaling, and explore its potential in immunotherapy. By elucidating the mechanisms through which MUC17 operates, researchers hope to uncover novel insights into disease mechanisms and identify new avenues for treatment in mucosal-associated conditions.
