Analytical Data
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基因名
MUC17
- Application
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别名
MUC3; Mucin Cell Surface Associated; Small intestinal mucin-3
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q685J3
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表达区间
Thr3773~Thr3998
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分子量
30kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MUC17 is a member of the mucin family of glycoproteins, which are characterized by their high glycosylation and large size, playing crucial roles in protective mucosal barriers in various tissues, particularly in the gastrointestinal tract. Research on MUC17 has garnered attention due to its involvement in various physiological and pathological processes, including inflammation and cancer progression. Specifically, MUC17 is expressed in epithelial cells, where it contributes to the formation of the protective mucous layer, thus playing a vital role in maintaining mucosal integrity. Its expression patterns have been observed to change in several diseases, including colorectal cancer, where it may facilitate tumor progression and metastasis. The interest in MUC17 as a therapeutic target has prompted studies aimed at understanding its structural and functional properties, which can aid in the development of diagnostic markers or potential therapeutic strategies. Recombinant MUC17 protein production has emerged as a vital tool in this research, enabling scientists to study its interactions with other molecules, assess its role in cell signaling, and explore its potential in immunotherapy. By elucidating the mechanisms through which MUC17 operates, researchers hope to uncover novel insights into disease mechanisms and identify new avenues for treatment in mucosal-associated conditions.












