Analytical Data
-
基因名
TAF1
- Application
-
别名
NSCL2; OF; BA2R; CCG1; CCGS; P250; TAF2A; KAT4; DYT3/TAF1; TAF1 RNA Polymerase II; Dystonia 3; TBP-associated factor 250 kDa; Cell cycle gene 1 protein
-
种属
Human
-
表达系统
E. coli
-
标签
N-His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P21675
-
表达区间
Thr1379~Pro1636
-
分子量
34kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TAF1 (TATA-binding protein-associated factor 1) is a key component of the transcriptional machinery that plays a crucial role in the regulation of gene expression. As a part of the mediator complex in eukaryotic cells, TAF1 influences RNA polymerase II activity by interacting with a variety of transcription factors and co-regulators. Recent studies have highlighted its involvement not only in basic transcription processes but also in cellular responses to stress and the regulation of cell cycle progression. Mutations or dysregulation of TAF1 have been implicated in various diseases, including cancer, neurodegenerative disorders, and other genetic conditions. The interest in TAF1 recombinant proteins stems from its potential therapeutic applications and the need for a deeper understanding of its functionalities. By producing TAF1 in recombinant systems, researchers aim to investigate its structural properties, functional interactions, and the mechanisms underlying its role in transcriptional regulation. This research holds promising implications for the development of targeted therapies that could modulate TAF1 activity and influence disease outcomes, thus making TAF1 a focal point in the fields of molecular biology and therapeutic development.
