Analytical Data
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Gene name
PKIb
- Application
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Alternative Names
PKI-B; PRKACN2; CAMP-Dependent Protein Kinase Inhibitor Beta
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9C010
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Expression Region
Met8~Glu76
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Molecular Weight
15kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PKIb (Protein Kinase B isoform beta) is a pivotal member of the AGC protein kinase family, primarily implicated in the regulation of various cellular processes, including metabolism, growth, and apoptosis. Its dysregulation has been associated with numerous diseases, particularly cancer and diabetes, making it a significant target for therapeutic intervention. Research on PKIb has focused on its structural attributes and signaling pathways, which are crucial for understanding its function and developing inhibitors. The study of PKIb recombinant proteins has become instrumental in elucidating these mechanisms, enabling researchers to investigate its enzymatic activity, interaction with substrates, and the influence of post-translational modifications. Utilizing recombinant DNA technology, scientists can produce large quantities of PKIb for biochemical assays and structural analyses. This approach not only facilitates the study of PKIb’s role in cellular signaling but also aids in the identification of potential drug candidates aimed at modulating its activity. Consequently, exploring PKIb through recombinant protein studies contributes significantly to the broader understanding of cellular signaling networks, paving the way for innovative therapeutic strategies in managing related diseases.
