Analytical Data
-
基因名
RAB17
- Application
-
别名
AW413472; FLJ12538; OTTHUMP00000164417; OTTHUMP00000202805; Rab 17; Rab17; RAB17 member RAS oncogene family; RAB17_HUMAN; Ras related protein Rab 17; Ras related protein Rab17; Ras-related protein Rab-17
-
种属
Human
-
表达系统
E. coli
-
标签
N- GST
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9H0T7
-
表达区间
1-212aa
-
分子量
50.5 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAB17 is a member of the RAS oncogene family, primarily involved in intracellular vesicle trafficking and sorting processes. Research has shown that RAB17 plays a crucial role in various cellular functions, including endocytosis, exocytosis, and the maintenance of cellular morphology. Its expression is particularly noteworthy in epithelial tissues, where it influences the transport of proteins and lipids essential for cell polarization and function. Studies have indicated that alterations in RAB17 expression levels are associated with several pathological conditions, including cancer, where it may contribute to tumor progression and metastasis by altering the cellular microenvironment. Additionally, RAB17's involvement in the immune response suggests that it may play a role in inflammatory diseases. Given its critical functions and implications in disease, the production of RAB17 recombinant proteins enables researchers to investigate its biochemical properties, interactions with other cellular components, and potential as a therapeutic target. By better understanding RAB17's mechanisms, scientists aim to explore its potential roles in disease processes and develop strategies for intervention, highlighting the significance of studying this protein in both basic and applied research contexts.
