Analytical Data
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Gene name
ENDO VIII
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简介
ENDO VIII Protein, crucial in genetic recombination, DNA repair, and replication, performs essential activities like pairing and strand-transfer. It contributes to maintaining genomic integrity and forms intricate molecular networks by interacting with dda and gene 32 proteins. As a member of the RecA family, ENDO VIII Protein underscores its significance in broader cellular mechanisms related to DNA dynamics and genome stability. ENDO VIII Protein, E. coli (His) is the recombinant E. coli-derived ENDO VIII protein, expressed by E. coli , with N-6*His labeled tag. ENDO VIII Protein, E. coli (His), has molecular weight of ~44 kDa.
- Application
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Species
E.coli
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Source
E. coli
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Tag
N-6*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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AA Sequence
MSDLKSRLIKASTSKLTAELTASKFFNEKDVVRTKIPMMNIALSGEITGGMQSGLLILAGPSKSFKSNFGLTMVSSYMRQYPDAVCLFYDSEFGITPAYLRSMGVDPERVIHTPVQSLEQLRIDMVNQLDAIERGEKVVVFIDSLGNLASKKETEDALNEKVVSDMTRAKTMKSLFRIVTPYFSTKNIPCIAINHTYETQEMFSKTVMGGGTGPMYSADTVFIIGKRQIKDGSDLQGYQFVLNVEKSRTVKEKSKFFIDVKFDGGIDPYSGLLDMALELGFVVKPKNGWYAREFLDEETGEMIREEKSWRAKDTNCTTFWGPLFKHQPFRDAIKRAYQLGAIDSNEIVEAEVDELINSKVEKFKSPESKSKSAADLETDLEQLSDMEEFNE
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Molecular Weight
44 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ENDO VIII is a recombinant protein that has garnered attention in recent years due to its potential applications in various fields, including biotechnology and pharmaceuticals. Initially identified in certain viral systems, ENDO VIII plays a crucial role in DNA repair mechanisms by assisting in the removal of damaged nucleotides, thereby maintaining genomic stability. The increasing prevalence of genetic disorders and the demand for innovative therapeutic strategies have fueled research into ENDO VIII. Scientists are particularly interested in its enzymatic properties, which could be harnessed for gene editing technologies, potentially improving the efficiency and specificity of tools like CRISPR. Moreover, by understanding the structural and functional characteristics of ENDO VIII, researchers aim to develop novel drugs or biologics that can target specific cellular pathways involved in cancer progression or other diseases linked to DNA damage. The recombinant production of ENDO VIII allows for a detailed study of its mechanisms and interactions, ultimately paving the way for advanced therapeutic applications. As studies continue, ENDO VIII is positioned to contribute significantly to the fields of gene therapy and molecular medicine, highlighting the importance of ongoing research in elucidating the roles of such proteins in cellular processes.
